Biofilm formation mechanism in pseudomonas aeruginosa and other bacteria and Quorum Sensing System

Abstract

Biofilm development and quorum sensing (QS) are closely interconnected processes. Biofilm refers to the complex, sessile communities of microbes found either attached to a surface or buried firmly in an extracellular matrix as aggregates. QS is a cell-cell communication mechanism that synchronizes gene expression in response to population cell density. Our aim is to determine the stages of biofilm formation, the role of the quorum sensing system in its creation, and how the quorum sensing system is in qram negative and positive bacteria.